Q: We've got some error messages during a table alignment process:
English: Error during file access (Error no. 1; system error no. 121: Error 121: The semaphore timeout period has expired.)
German: Fehler beim Zugriff auf Datei "\\server\share$\1049.040"! (Fehler No. 1; Systemfehler Nr. 121: Das Zeitlimit für die Semaphore wurde erreicht.) 

A: This is caused by a network problem. In most cases there is a conflict between the network adapters and the network switch. You should solve this by checking the AutoSensing mode of the ports of the network adapter and the network switch.
There is a entry inside Microsoft's knowledge base concerning this topic: http://support.microsoft.com/?scid=kb%3Ben-us%3B325487&x=5&y=11